Multi-effect WFI Stills

3rd Generation Multi-effect Stills for WFI & Pure Steam

Units engineered for optimised performance and safe distillate quality, exceeding the latest USP/EP
requirements for Water for Injection (WFI). Pure steam can be produced from the first column when required.

Design features

  • Fully automatic operation and surveillance
  • Unique 4-stage droplet separation
  • High operational safety and flexibility
  • Pure steam from the 1st column
  • Space-saving footprint and easy installation

Multi-effect stills — steam heated
Type & columns Steam pressure (bar g) Production (L/h)
S-100-3 / S-100-4 3–8 100–200
S-200-3 / S-200-4 3–8 200–400
S-300-4 / S-300-6 3–8 300–600
S-500-4 / S-500-6 3–8 500–1 100
S-1000-5 / S-1000-6 4–8 1 200–2 100
S-2000-5 / S-2000-6 4–8 2 800–4 100
S-3000-6 / S-3000-8 5–8 4 400–6 200
S-4000-6 / S-4000-8 5–8 5 800–8 000

Multi-effect stills — electrically heated
Type & columns Power (kW) Production (L/h)
E-100-3 28 100
E-200-4 44 200
E-300-4 65 300
E-500-6 74 500

PLC-automated standard functions

  • Automatic start/stop via external signal and manual start/stop
  • Automatic pressure control to selected setpoint
  • Automatic valve regulation of heating steam, feed water and compressed air
  • Continuous surveillance and alarms for critical process values

Examples of optional equipment

  • Automated or manual valves for pure-steam production
  • Pure-steam sample condenser
  • Sterile air vent filter with close-off
  • Self-sterilisation cycle and valves
  • Heating-steam safety relief valve and pressure shut-off
  • Distillate after-cooler to target temperature
  • Electropolished internal surfaces
  • Borescope inspection of internal welds
  • Central control cabinet for the complete WFI system
  • WFI storage tanks and distribution loops

Documentation & validation

All AQUA-NOVA® stills and pure-steam generators undergo factory acceptance testing (FAT) before delivery.
Tests are documented and, when applicable, produced steam quality is verified by an independent laboratory.
Software is developed according to GAMP guidelines. On request, full Pre-IQ and OQ documentation is supplied,
including calibration records, pressure-vessel drawings, material/weld certificates, and complete mechanical/
electrical/instrumentation manuals.

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TWO in ONE – Pure Steam & WFI Production The growing demand for flexibility calls for innovative technical solutions. Traditionally, multi-effect stills can produce only limited quantities of pure steam from the first column while distilling WFI. The unique AQUA-NOVA® design, however, enables the production […]